Custom Peptides
Cayman Chemical N 8ZHeptadecen1ylO 3p 10mg
A synthetic macamide that irreversibly inhibits FAAH with an IC50 value of 0.153 µM
Cayman Chemical ncrox-5methnsulfonate 10mg
A cell permeable inhibitor of necrosis that also demonstrates strong mitochondrial reactive oxygen species and ONOO- scavenging activity; localizes in mitochondria, selectively blocking oxidative stress-induced necrotic cell death (0.1 μM necrox-5 inhibited ~50% cell death in H9C2 cells exposed to 400 μM t-BHP)
Cayman Chemical -Glu-PhetrIfluoroACTAte100mg
A dipeptide with metabolism-altering activity; prevents increases in lipid accumulation in oleic acid-stimulated AML12 hepatocytes at 30 µM; increases CaSR levels and secretion of CCK and GLP-1 in STC-1 enteroendocrine cells at 2.5-10 mM; changes in urine levels are associated with hypertension and PKU; changes in serum levels are associated with prostate cancer
Cayman Chemical Cardol dIen 10mg
A phenol from cashew nut shell liquid; kills 50, 100, 100, and 100% of S. mansoni worms after 24 hours when used at concentrations of 25, 50, 100, or 200 µM, respectively; LC50 = 32.2 µM after 24 and 48 hours against S. mansoni worms; has been used as a starting material for the synthesis of bis-benzoxazines
Cayman Chemical UR144 Degradnt NpentnoIc 10mg
A potential phase I metabolite of a degradation product observed during GC-MS analysis of samples containing UR-144; intended for forensic and research applications
Cayman Chemical Cembrenediol 10mg
A diterpenoid from tobacco plants; inhibits induction of EA-EBV by TPA in vitro (IC50 = 21.9 μM); inhibits tumor promoting effects of TPA on 7,12-demethylbenz[a]anthracene-induced papilloma formation in vivo; exerts autotoxicity and phytotoxic activity against L. sativa seedlings
Cayman Chemical 2C-ThydrochlorIde 10mg
A member of a family of 2,5-dimethoxy phenethylamines, substituted on the four position of the aromatic ring with an methylthio group; intended for forensic and research purposes
Cayman Chemical IsogInkgetIn 10mg
A biflavonoid inhibitor of pre-mRNA splicing; reduces the activity of an mRNA-dependent luciferase reporter, shifts the total RNA extract from predominantly mRNA to pre-mRNA, and arrests cell growth in HEK293 cells at 33 μM; suppresses Con A- and LPS-induced mouse lymphocyte proliferation at 10 μM; suppresses PMA- and A23187-induced arachidonic acid release in rat peritoneal macrophages at 10 μM; dose-dependently reduces MMP-9 activity, expression, and mRNA levels in and decreases cell invasion by HT1080 fibrosarcoma cells from 5-20 μM
Cayman Chemical MTYL 5 6 7 8ttradehyDR R 10mg
An internal standard used in the quantitative analysis of risperidone
Cayman Chemical ItoprIdehydrochlorIde 10mg
An AChE inhibitor (IC50 = 1.6 µM for rat stomach enzyme) and a prokinetic agent; induces contractions in isolated rabbit duodenum from 1-100 µM; enhances ACh-induced contractions in isolated guinea pig stomach circular muscle strips; enhances normal gastric antral motility and improves clonidine-induced gastric antral hypomotility and delayed gastric emptying in rats at 100 mg/kg
Cayman Chemical ScutelarIa WogonsIde 10mg
A flavonoid with anti-inflammatory and anticancer activities; an active metabolite of wogonin; decreases colonic pathological damage and myeloperoxidase and iNOS activity, as well as inhibits NF-κB and NLRP3 inflammasome activation in a DSS-induced mouse model of colitis at 25 and 50 mg/kg; inhibits phosphorylation of mTOR, as well as inhibits the growth of (IC50 = 133.9 µM), and induces autophagy in, MDA-MB-231 breast cancer cells; inhibits tube formation by HUVECs, increases Wnt3a levels and β-catenin phosphorylation in MCF-7 cells at 50-100 µM; reduces tumor growth and angiogenesis in an MCF-7 mouse xenograft model at 80 mg/kg
Cayman Chemical LIpoxamycInhemIsulfate 10mg
A serine palmitoyltransferase inhibitor (IC50 = 21 nM for the S. cerevisiae enzyme) and antifungal agent; inhibits human SPT with an IC50 value ~10-fold lower than the S. cerevisiae enzyme; active against several species of Candida and Cryptococcus, as well as S. cerevisiae (MICs = 0.5-16, 0.25-0.5, and 16 UG/ml, respectively)
Cayman Chemical DexmedetomIdIn 10mg
An α2-AR agonist; selectively binds to α2-ARs over α1-ARs (Kis = 0.015 and 5 nM, respectively); prevents increases in CTnI, as well as reduces myocardial apoptosis, pyroptosis, and ferroptosis in a mouse model of CLP-induced sepsis at 50 UG/kg; induces sedation and decreases mechanical nociception in cats at 40 UG/kg
Cayman Chemical 1Docosahexaenoyl2hydroxys 10mg
A lysophospholipid; has been found in shark liver extract; decreases LPS-induced increases in the levels of TNF-α and IL-6 in RAW 264.7 cells; decreases LPS-induced NO production in RAW 264.7 cells from 12-200 µM; inhibits zymosan A-induced plasma leakage into the peritoneum in a mouse model of peritonitis from 15-500 UG/kg
Cayman Chemical GInkgolIde B 10mg
A potent PAFR antagonist that inhibits platelet aggregation at concentrations from 10-500 μM; demonstrates anticancer, anti-inflammatory, anti-allergic, antioxidant, and neuroprotective effects